G protein-coupled receptors (GPCRs) are the largest and most versatile family of transmembrane receptors in the cell and they play a vital role in the regulation of multiple physiological processes.The family Miridae (Hemiptera: Heteroptera) is one of the most diverse families of insects.Until now, information on GPCRs has been lacking in Miridae.A
Abstract Although mitochondrial DNA has been widely used in phylogeography, evidence has emerged that factors such as climate, food availability, and environmental pressures that produce high levels of stress can exert a strong influence on mitochondrial genomes, to the point of promoting the persistence of certain genotypes in order to compensate
Abstract Background Strings Targeting glucose uptake by glucose transporter (GLUT) inhibitors is a therapeutic opportunity, but efforts on GLUT inhibitors have not been successful in the clinic and the underlying mechanism remains unclear.We aim to identify the key metabolic changes responsible for cancer cell survival from glucose limitation and e
ABSTRACT Objective: To highlight the importance of the new classification criteria for the macrophage activation syndrome (MAS) Intake in systemic juvenile idiopathic arthritis in order to reduce morbidity and mortality outcome related to this disease.Case description: A 12-year-old female patient with diagnosis of systemic juvenile idiopathic arth